The Mammalian Endocannabinoid System - What is it?

on February 12, 2019

The mammalian endocannabinoid system is a unique part of the body belonging to every mammal on the planet. Some researchers and medical professionals are starting to look at the endocannabinoid system or ECS for short as the bridge between the mind and body. 

The endocannabinoid system plays a pivotal role in promoting healthy regulatory functions throughout the human body. The ECS works in conjunction with multiple cannabinoid receptors such as CB1 receptors, CB2 receptors, THRV receptors, and others. It's through the use of these receptors that the ECS absorbs phytocannabinoids such a CBD. 

The absorption of phytocannabinoids such as CBD, THC, CBN, CBG, and others help facilitate more efficient body functions. Consumers and medical patients experience a wide array of different benefits from consuming phytocannabinoids. 

As of January 2019, there are 33 states in America with legal access to medical cannabis. Also, 10 states have legal access to adult use recreational cannabis markets. The entire country, however, has access to 100% legal hemp derived CBD. This means that anyone and everyone could stand to benefit from CBD in one form or another potentially.

What Exactly is the Endocannabinoid System?

The mammalian ECS is comprised of lipid-based endogenous retrograde neurotransmitters that attach to cannabinoid receptors (CB1 and CB2). It also consists of cannabinoid receptor proteins which are found to be expressed in our central nervous system. 

As more research is being conducted on phytocannabinoids and our endocannabinoid system a deeper understanding of its essential role is becoming clear. Medical professionals, scientists, and researchers are beginning to recognize the ECS as a vital modulatory system for facilitating healthy function in the endocrine system, brain, and immune tissues. 

The ECS is also showing that it has an incredibly vital regulatory role in responses to stress, reproduction functions, and the secretion of hormones throughout our body per a research paper published on the NCBI titled, "The role of the endocannabinoid system in the regulation of endocrine function and in the control of energy balance in humans." 

This study goes on to explain many different factors about the ECS. It also ends on a note saying; 

"It is, therefore, possible to speculate about the future clinical use of CB1 antagonists, as a means of improving gonadotrophin pulsatility and fertilization capacity as well as the prevention of cardiovascular disease and type 2 diabetes mellitus."

When was the Endocannabinoid System Discovered?

Based on the way things are going today you would think that CBD and the endocannabinoid system were just discovered. That's not the case though. While the endocannabinoid system is a relatively new discovery that took place in the early 1990s cannabinoids such as CBD and THC have been known about for many decades. 

The discovery of phytocannabinoids such as CBD and THC started in the late 1930s and early 1940s. While many people give credit to Israeli researcher Raphael Mechoulam, he was just going off of research done by others before him. 

Little known to most people an American organic chemist by the name of Rodger Adams who during WWl and WWll served as a high-level scientist for the United States was the first to isolate CBD. Roger was awarded a patent based on his method of isolating CBD in 1942. 

Roger Adams also should be given the appropriate credit for becoming the first researcher to identify tetrahydrocannabinol successfully. Not only did he identify it he also made a point in the American Journal of Chemistry to publish studies regarding the subject, 27 of them in fact.

The Future of ECS Education for Medical Professionals

As research continues to advance regarding the endocannabinoid system medical professionals are finally being taught about this vital part of our body in med school. It's estimated that as of 2019 only roughly 13% of med school students learn about this essential part of our anatomy. 

It will take time for science and medicine to catch up with industry. Encourage your doctor, and other medical professionals to learn about the Endocannabinoid System as well as require it to be a standard part of the teachings for all med students. 

The lack of knowledge and information our medical community has regarding the mammalian endocannabinoid system has in part been responsible for the terrible opioid epidemic the world is facing today. 

People may have used these drugs, but it's doctors prescribing them that have truly aided the epidemic. There is a better way, and it seems our endocannabinoid system will play a vital role in improving the quality of life for people globally.